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MEDICAL ONCOLOGY

Overview

With the rising number of cancer patients and with the need for comprehensive cancer care facility, the Department of Medical Oncology, at Amala Institute of Medical Sciences, offers a wide range of cancer treatment options, having a well-equipped team of highly qualified Medical Oncologists and Haemato-oncologists experienced in diagnosis, treatment planning, Chemotherapy procedures, targeted therapy, Bone marrow Transplantation and Hormonal Therapy to all patients of all age groups with solid organ tumors and Haematological malignancies.The department also owns a well-equipped Bone marrow transplant unit, which started rendering services from Dec 2021, and aims at delivering utmost cost-effective care to the transplant patients, with inclusion of the best possible infrastructure and facilities.The Medical Oncology department also has a well-functioning Clinical Research Unit (CRU), which hosts three different types of Govt. funded projects (NOCI-BIRAC, HCC & ICMR-HBCR), mainly focusing on cancer registry and conducting clinical trials.

Facilities

  • Systemic therapy of all cancers
    •  Chemotherapy
    • Immunotherapy
    •  Targeted therapy
  • Paediatric oncology
  • Paediatric and adult leukemia unit

  • Precision oncology
  • Day care therapy unit and Procedure room
  • Bone marrow transplantation Unit Autologous
  • Allogenic

    Related 

    Maternal unrelated

     Haploidentical donor transplantion

  • Neutropenia ICU with Semi ICU facility
  • Clinical research unit
  • Molecular oncology lab
  • Comprehensive cancer registry

Services

 services available on all working days from 8:00AM to 4:00PM

Special evening OPD facility available on specific days in a week from (5:00PM TO 7:00PM)

Various speciality clinic services including breast clinic , Head and neck clinic, Genitourinary, Gynaec oncology clinic, GIT clinic, chest clinic and other clinical services available with the aim of delivering the best possible updated treatment.

 Various OPD procedures such as bone marrow aspiration and biopsy, blood and blood product transfusions, central line care, dressings etc are being carried out in a well facilitated set up by well trained doctors and nursing staff.

Different chemotherapy protocols are being delivered on a day care basis for which department owns a ( 17 bedded) day care chemotherapy room with well trained staffs functioning from morning 9:00Am to 4:00pm on all working days.

Department of Medical Oncology is also equipped with an ICU which functions exclusively with well trained ICU nursing and supportive staff. for handling neutropenia and other oncological emergencies.

Department is updated with Bone marrow transplantation unit which handles both autologous and allogenic transplants , aiming at delivering utmost cost effective and high quality care to all the transplant patients.

 The department also has a well-functioning Clinical Research Unit (CRU) which hosts different types of projects (NOCI-BIRAC, HCC &

ICMR-HBCR). CRU also handles hospital based cancer registry and clinical trials , which offer a great opportunity for cancer patients in getting the latest treatment.

 The department of Medical oncology is the first in private sector, under the Kerala University of Health Sciences to get approval for an annual intake of DM seats per year. The department provides one of the best evidence based training in the subject with various other academic activities like clinical discussion, journal clubs, presentations and discussions.

 As this institute is a comprehensive cancer centre, alll the complicated oncology cases are discussed in detail for planning the best treatment in a multidisciplinary board consisting of medical oncologists, surgical oncologists, radiation oncologists, pathologists, radiologist

Faculties

Dr Anilkumar Thazhatha Jose
Reg.No: TCMC 17508
Professor & HOD
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Dr. Sunu Lazar Cyriac
Reg.No: TCMC 29434
Associate Professor
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Dr Ashwin Oommen Philips
Reg.No: KSMC 39765
Associate Professor
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Dr. Unnikrishnan P
Reg.No: TCMC 44642
Assistant Professor
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CME

CME Details Date of Conduct
Name : Medical Research Seminars
Theme/Subject : An Overview and common pitfalls
Credit Hours : 1

2024
Name : De-Code R: Mastering the essentials
Theme/Subject : Learn the fundamentals of research, master data manipulation technique, statistical analysis
Credit Hours : 8.30am-5.00pm

2024
Name : Research Grant Writing Workshop
Theme/Subject : An Empowering workshop on Research Grant Writing , Learn essentials skills,Gain insights from experts

2024
Name : Amala Hemato-Oncology Conference 2023
Theme/Subject : 1. Stem Cell transplantation in developing countries 2. Lymphoma 3. Multiple Myeloma 4. Neutropenic Care 5. BMT Unit from nursing perspectives
Credit Hours : 1.5

2023
Name : Molecular method and precision Oncology -an introducing course -7
Theme/Subject : Cell biopsy

2022
Name : Amala Cancer Registry Annual meeting
Theme/Subject : Cancer Registry

2021
Name : Crossroads-2021
Theme/Subject : Career guidance workshop

2021
Name : ABCC-2020
Theme/Subject : CARCINOMA BREAST

2020
Name : ABCC-2020
Theme/Subject : CARCINOMA BREAST

2020

Publications

  • No family should suffer from cervical cancer twice – the palliative care role in HPV prevention; Iyengar S, Kantor K, Cyriac S, Remadevi K, Usha V, Robinson S, Rani A, Rajagopal MR, Broderick A.J Pain Symptom Manage. 2021 Jul 10;S0885-3924(21)00420-6
  • Effect of pre-transplant JAK1/2 inhibitors and CD34 dose on transplant outcomes in Myelofibrosis;Sunu Cyriac, Shruti Prem, AuroViswabandya et al; Eur J Haematol. 2021 Jul 14. doi:10.1111/ejh.13689. Online ahead of print
  • Research Biopsies in patients with gynecologic cancers: patient-reported outcomes, perceptions and preferences; AinhoaMadariaga, Sunu Cyriac,Amit M. Oza, Stephanie Lheureux,doi.org/10.1016/j.ajog.2021.06.071; Available online 23 June 2021
  • HPV vaccine: Expanding indications and global disparity. Christina Uwins, Sunu Cyriac, GeetuBhandoria; Vaccine2021 Jun 29;39(29):3787-3789
  • Retrospective Analysis of Early Impact of COVID-19 on Systemic Cancer Treatment—A Pilot Study; Sunu L Cyriac, AnakhaPattiyeil, Febin Antony. Indian Journal of Medical and Paediatric Oncology 2021; 42(01): 015-020; DOI: 10.1055/s-0041-1730239
  • Updates on systemic therapy for cervical cancer (invited review-accepted for publication in Gynecology and breast cancer special edition, Jan 2021). Cyriac S,Gopu P, Antony F, Oza A M, KarakasisK; Ind J Med ResJan 2021
  • Knowledge, Attitude and Practice of Indian Oncology Residents on Clinical Trials: An Observational StudyRanjith Kumar CS*, SmitaKayal, Biswajit Dubashi,Cyriac S et al. J cancer Clin Trials;Volume 5:3, 2020
  • Delivery of Cancer Care in India and Canada: Opportunities for Bidirectional Learning, Cyriac S, Booth CM. J Glob Oncol. 2019 Oct;5:1-5
  • Late Effects of Breast Cancer Treatment and Outcome after Corrective Interventions.Pillai US, Kayal S, Cyriac S, Nisha Y, Dharanipragada K, Kamalanathan SK, Halanaik D, Kumar N, Madasamy P, Muniswamy DK, Dubashi B. Asian Pac J Cancer Prev. 2019 Sep 1;20(9):2673-2679
  • Optimizing the Care of Malignant Bowel Obstruction in Patients With Advanced Gynecologic Cancer.Lee YC, Jivraj N, Wang L, Chawla T, Lau J, Croke J, Allard JP, Stuart-McEwan T, Nathwani K, Bowering V, Karakasis K, O'Brien C, Shlomovitz E, Ferguson SE, Buchanan S, Ng P, Cyriac S, Tinker L, Dhani N, Oza AM, Lheureux S. J Oncol Pract. 2019 Dec;15(12):e1066-e1075
  • POEMS Syndrome: Indian Experience From a Tertiary-Care Institute; Pramanik A, S Cyriac, L Kumar et al, Clin Lymphoma Myeloma Leuk. 2019 May 29. pii: S2152-2650(19)30062-X
  • S Cyriac, A Garcia-Horton, , J Mattsson, FV Michelis et al; Patient age and donor HLA matching can stratify allogeneic hematopoietic cell transplantation patients into prognostic groups; Eur J Haematol, 2022 Aug 26 DOI: 10.1111/ejh.13850
  • Sunu Cyriac, Varun Narayan; Marked New Bone Formation on Treatment of Multiple Myeloma; Mayo Clin Proc, 2022; doi: 10.1016/j.mayocp. 2022.03.002
  • Al-Shaibani E, Cyriac S, Michelis Fotios V, et al; Comparison of the Prognostic Ability of the HCT-CI, the Modified EBMT, and the EBMT-ADT Pre-transplant Risk Scores for Acute Leukemia; Clin Lymphoma Myeloma Leuk. 2021 Jun. doi: 10.1016/j.clml.2021.01.022
  • Cyriac S, Katherine Karakasis, Amit M. Oza; Rucaparib for the treatment of ovarian cancer; Expert Opinion on Orphan Drugs Vol 6, 2018 - Issue 2
  • Cyriac S, Amit M. Oza, K Karakasis; DNA Repair Defects for Therapy in Ovarian Cancer: The BRCA1/ 2 and PARP Inhibitor Story; Ind J Gynec Oncol 2017 Doi 10.1007/s40944-017-0155-8
  • Rajagopal MD, Kar R, Basu D, Cyriac SL et al; Composite lymphoma with coexistence of diffuse large B-cell lymphoma and anaplastic large cell lymphoma: Diagnostic pitfalls; Ind J Pathol Micro. 2017;doi: 10.4103/IJPM.IJPM_139_16
  • Pillai, U, Cyriac, S, Badhe, B. et al; Impact of Oncologist Initiated Selective Review of Pathology Specimens in Multidisciplinary Onco-pathological Discussions on the Management of Malignancies in a University Hospital in India; J of Adv in Med and Medical Res 2016 https://doi. org /10. 9734/BJMMR/2016/27156
  • Ramakrishnaiah VP , Kotlapati S, Cyriac S et al; Palliation of Dysphagia in Carcinoma Esophagus, Clin Med Insights Gastroenterol 2016; doi: 10.4137/CGast.S30303
  • Jain D, Cyriac S, Mathur SR, Kumar L, Guleria R et al; Evaluation of epidermal growth factor receptor mutations based on mutation specific immunohistochemistry in non-small cell lung cancer: A preliminary study; Ind J Med Res. 2016. doi: 10.4103/0971-5916.182621
  • Dhanraj KM, Kayal S, Cyriac S. et al; Comparison of efficacy of neoadjuvant chemotherapy FEC 100 and Docetaxel 75 versus AC and Docetaxel in locally advanced breast cancer: a randomized clinical study; Med Oncol 2015 Dec; doi: 10.1007/s12032-015-0697-5
  • Cyriac S, Walia R, Suri V, Bakhshi S; Colonic Malignant Peripheral Nerve Sheath Tumor in a Child; J Ped Hemat/Oncol: Nov 2014; doi: 10.1097/ MPH.0b013e318290bc9f
  • Kayal S, Sharma A, Tejomurtula T, Cyriac S, Raina V. et al; High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Multiple Myeloma: A Single Institution Experience at All India Institute of Medical Sciences, New Delhi, Using Non-Cryopreserved Peripheral Blood Stem Cells. Clin Lymp Myel Leuk. 2014. Doi:10.1016/j.clml.2013.09.001
  • Kumar L, Cyriac S, Sharma O, et al; Autologous Stem Cell Transplantation for Multiple Myeloma: Identification of Prognostic Factors; Clin Lymp Myel Leuk 2013; doi:10.1016/j.clml.2012.08.007
  • Gauri Kapoor, Sunu Lazar Cyriac, V P Gangadharan, Prashant Mathur et al; Profile of Childhood Cancers From Hospital-Based Cancer Registries in India, 2012-19; Indian Pediatr. 2024 Jan 15;61(1):39-44.
  • Unnikrishnan P, Nair SG, Sugeeth MT, Benson R, Mony RP. Cutaneous Metastasis from Sacral Chordoma: A Case Report. IJBC 2019; 11(3): 109-110.
  • Puthillathu Unnikrishnan, Geetha Narayanan, Bhavya S. Kumar, and Nandini Devi. B-lymphoblastic lymphoma of the rectum. Proc(Bayl Univ Med Cent) 2017; 30(3): 336–337
  • Geetha Narayanan, Unnikrishnan P, Bhavya S. Kumar. Hypercalcemia and osteolytic lesion as presenting feature in an adult ph positive acute lymphoblastic leukemia patient mimicking multiple myeloma. ejpmr, 2017,4(03), 490-491.
  • Joseph R, Anoop TM, Unnikrishnan P. Carcinoma breast with ectopic intrathoracic thyroid tissue: A rare presentation. Indian J Med Paediatr Oncol 2020;41:758-60
  • Rakul Nambiar K, Rona Joseph P, Unnikrishnan P, Geetha N. Non Hodgkin’s lymphoma of the scalp - A case report. Sch J Med Case Rep 2016; 4(6):376-378
  • Sugeeth MT, Vishnu H, Unnikrishnan P. Geetha N. Non-Hodgkin’s Lymphoma of the Hard Palate - A Case Report. Sch J Med Case Rep 2016; 4(7):469-470
  • Danish E, Vishnu H, Unnikrishnan P, Sharath K Krishnan, T.M. Anoop. A case of fibro muscular dysplasia with abdominal aortic aneurysm. Sch J Med Case Rep 2016; 4(6):376-378.
  • Anoop T. M, Bhavya S Kumar, Gayatri Gopan, Unnikrishnan P. Retroperitoneal Evans Tumour. Sch J Med Case Rep 2017; 5(1):22-23
  • Anoop TM, Joseph R, Unnikrishnan P, Thomas F, Venugopal M. Taxane induced acute interstitial pneumonitis in patients with breast cancer and outcome of taxane rechallenge. Lung India 202
  • Ashwin P, Venkatraman et al- Efficacy of Single Dose Rasburicase (1.5 mg) for Prophylaxis and Management of Laboratory Tumor Lysis Syndrome, Indian Journal of Hematology and Blood Transfusion 34(1) · March 2018
  • Ashwin P, Venkatraman et al -Experience with pemetrexed maintenance with NSCLC from tertiary level hospital.Dr MGR University e-journal.
  • Eqbal A, Goodliffe L, Masoom H, Ashwin P et al. The Syncopal Sarcoma. J Am Coll Cardiol Case Rep. 2022 Aug, 4 (16) 1037–1041
  • Mall A, Negi P, Philip AO, Kingsley PA. Induction chemotherapy in head and neck cancers – Boon or bane? J Can Res Ther 2023;19:420-5.
  • Philips A, Soumya P, Sunu C, Moharana, et al Real-World Experiences of Next-Generation Sequencing in Oncology: From an Indian Multicenter Registry andCollaborative Centers. Indian Journal of Medical and Paediatric Oncology. 10.1055/s-0044-1779275.